Marcus D. Goncalves, Changyuan Lu, Jordan Tutnauer, Travis E. Hartman, Seo-Kyoung Hwang, Charles J Murphy, Chantal Pauli, Roxanne Morris, E Carl Lekaye, Steven S. Gross, Kyu Y. Rhee, Lewis C. Cantley, and Jihye Yun.  High-Fructose Corn Syrup Enhances Intestinal Tumor Growth. Science, in press
Expected March 20 2019

 Marcus D. Goncalves*, Benjamin D. Hopkins*, and Lewis C. Cantley. Dietary Fat and Sugars in Promoting Cancer Development. Annu Rev Cancer Biol, in press Expected March 4, 2019, *authors contributed equally

Cheson BD, O'Brien S, Ewer MS, Goncalves MD, Farooki A, Lenz G, Yu A, Fisher RI, Zinzani PL, Dreyling M. Optimal Management of Adverse Events From Copanlisib in the Treatment of Patients With Non-Hodgkin Lymphomas. Clin Lymphoma Myeloma Leuk. 2019 Mar;19(3):135-141. doi: 10.1016/j.clml.2018.11.021. Epub 2018 Nov 29.

Cindy Hodakoski, Benjamin D. Hopkins, Guoan Zhang, Taojunfeng Su, Zhe Cheng, Roxanne Morris, Kyu Y. Rhee, Marcus D. Goncalves, and Lewis C. Cantley. Rac-mediated macropinocytosis of extracellular protein promotes glucose independence in non-small cell lung cancer. Cancers 2019, 11(1), 37

2019


2018

Goncalves MD, Hwang SK, Pauli C, Murphy CJ, Cheng Z, Hopkins BD, Wu D, Loughran RM, Emerling BM, Zhang G, Fearon DT, Cantley LC. Fenofibrate prevents skeletal muscle loss in mice with lung cancer. Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E743-E752. 

Goncalves MD, Taylor S, Halpenny DF, Schwitzer E, Gandelman S, Jackson J, Lukose A, Plodkowski AJ, Tan KS, Dunphy M, Jones LW, Downey RJ. Imaging skeletal muscle volume, density, and FDG uptake before and after induction therapy for non-small cell lung cancer. Clin Radiol. 2018 May;73(5):505.e1-505.e8.

Lundquist MR, Goncalves MD, Loughran RM, Possik E, Vijayaraghavan T, Yang A, Pauli C, Ravi A, Verma A, Yang Z, Johnson JL, Wong JCY, Ma Y, Hwang KS, Weinkove D, Divecha N, Asara JM, Elemento O, Rubin MA, Kimmelman AC, Pause A, Cantley LC, Emerling BM. Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy. Mol Cell. 2018 May 3;70(3):531-544.e9.

Hopkins BD, Pauli C, Xing D, Wang DG, Li X, Wu D, Amadiume SC, Goncalves MD, Hodakoski C, Lundquist MR, Bareja R, Ma Y, Harris EM, Sboner A, Beltran H, Rubin MA, Mukherjee S, Cantley LC. Suppression of insulin feedback enhances the efficacy of PI3K inhibitors. Nature. 2018 Jul 4.

Goncalves MD, Cantley LC. A Glycolysis Outsider Steps into the Cancer Spotlight. Cell Metab. 2018 Jul 3;28(1):3-4. doi: 10.1016/j.cmet.2018.06.017.

Darragh F Halpenny, Marcus Goncalves, Emily Schwitzer, Jennifer Golia Pernicka, Jasmyne Jackson, Stephanie Gandelman, Chaya S. Moskowitz, Michael Postow, Marina Mourtzakis, Bette Caan, Lee W Jones, Andrew J Plodkowski.  Computed tomography derived assessments of regional muscle volume: Validating their use as predictors of whole body muscle volume in cancer patients. Br J Radiol, 2018; 91:20180451

Marcus D. Goncalves, Benjamin D. Hopkins, and Lewis C. Cantley. PI 3-Kinase, Growth Disorders, and Cancer. N Engl J Med 2018; 379:2052-2062


2017

Torigian DA, Green-McKenzie J, Liu X, Shofer FS, Werner T, Smith CE, Strasser AA, Moghbel MC, Parekh AH, Choi G, Goncalves MD, Spaccarelli N, Gholami S, Kumar PS, Tong Y, Udupa JK, Mesaros C, Alavi A. A Study of the Feasibility of FDG-PET/CT to Systematically Detect and Quantify Differential Metabolic Effects of Chronic Tobacco Use in Organs of the Whole Body-A Prospective Pilot Study. Acad Radiol. 2017 Aug;24(8):930-940.

Goncalves MD, Taylor S, Halpenny DF, Schwitzer E, Gandelman S, Jackson J, Lukose A, Plodkowski AJ, Tan KS, Dunphy M, Jones LW, Downey RJ. Imaging skeletal muscle volume, density, and FDG uptake before and after induction therapy for non-small cell lung cancer. Clin Radiol. 2018 May;73(5):505.e1-505.e8.

Goncalves MD, Green-McKenzie J, Alavi A, Torigian DA. Regional Variation in Skeletal Muscle and Adipose Tissue FDG Uptake Using PET/CT and Their Relation to BMI. Acad Radiol. 2017 Oct;24(10):1288-1294. doi: 10.1016/j.acra.2017.04.010. Epub 2017 May 24.

Torigian DA, Green-McKenzie J, Liu X, Shofer FS, Werner T, Smith CE, Strasser AA, Moghbel MC, Parekh AH, Choi G, Goncalves MD, Spaccarelli N, Gholami S, Kumar PS, Tong Y, Udupa JK, Mesaros C, Alavi A. A Study of the Feasibility of FDG-PET/CT to Systematically Detect and Quantify Differential Metabolic Effects of Chronic Tobacco Use in Organs of the Whole Body-A Prospective Pilot Study. Acad Radiol. 2017 Aug;24(8):930-940. 


Hopkins BD*, Goncalves MD*, Cantley LC. Obesity and Cancer Mechanisms: Cancer Metabolism. J Clin Oncol. 2016 Dec 10;34(35):4277-4283. Epub 2016 Nov 7. Review.
*authors contributed equally 

2016


2014


Lamming DW, Ye L, Katajisto P, Goncalves MD, Saitoh M, Stevens DM, Davis JG, Salmon AB, Richardson A, Ahima RS, Guertin DA, Sabatini DM, Baur JA. Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity.Science. 2012 Mar 30;335(6076):1638-43

2012


2011

Pistilli EE, Bogdanovich S, Goncalves MD, Ahima RS, Lachey J, Seehra J, Khurana T. Targeting the activin type IIB receptor to improve muscle mass and function in the mdx mouse model of Duchenne muscular dystrophy. Am J Pathol. 2011 Mar;178(3):1287-97. doi: 10.1016/j.ajpath.2010.11.071.


Goncalves MD, Pistilli EE, Balduzzi A, Birnbaum MJ, Lachey J, Khurana TS, Ahima RS. Akt deficiency attenuates muscle size and function but not the response to ActRIIB inhibition. PLoS One. 2010 Sep 15;5(9):e12707

2010


Akpan I*, Goncalves MD*, Dhir R, Yin X, Pistilli EE, Bogdanovich S, Khurana TS, Ucran J, Lachey J, Ahima RS. The effects of a soluble activin type IIB receptor on obesity and insulin sensitivity. Int J Obes (Lond). 2009 Nov;33(11):1265-73.
*authors contributed equally

2009